Professor Mercer is approached by his old friend CJ, a prominent investigative journalist who asks for help after she's poisoned with a rare and deadly nerve agent; with time running out, Mercer pieces together scant clues.
After a passenger plane crashes into the Potomac River, suspicions focus on the pilot; Professor Mercer and the team are asked to investigate the pilot's personal motivations, and piece together clues in the hope of revealing the truth.