I wouldn't recommend this movie but it's not terrible. Slow moving for the first half as they try to develop the story. An unfaithful husband is struggling to salvage his marriage with an exotic vacation. The wife reluctantly goes along and has all the fears hurt women feel about an unfaithful husband and finds forgiveness hard. They wind up on an isolated island (Hence, 'Isolation') with two other inhabited houses (High end almost mansions). They meet both couples separately and trust the wrong couple. Zero character development and everyone is shallow, brain dead, dopers. Everyone dies, except our couple, in horrible/goreful manners. Lots of unnecessary vulgarity and drug use. I won't watch it again and wouldn't have watched it in the first place knowing what I know now.