I have a DVD of four episodes of this series and it's quite entertaining. Bernie Kopell plays Buddy Overstreet's brother Albert. He appeared in Get Smart as well playing the head of KAOS. Leonard Stern also produced Get Smart. More similarities: David Ketchum, who appeared in Get Smart, also appeared in Run, Buddy Run. The very first episode was executive-produced by David Susskind but other episodes I have did not list him. The pill-taking Superhero was either Captain Nice or Mr. Terrific. These shows also include the network id (CBS) but did not include the original commercials. My copies were done from 16mm film. According to some information I have, Jack Sheldon is a musician and got his start in show-business as a musician and his son also is a musician now. When watching this, it reminded me of the naiveté of Will Ferrell's character in "Elf" and Jack Sheldon looked a little like Will Ferrell in that movie. Buddy Overstreet appears to be a simpleton.
Review of Run Buddy Run
