Sahira refuses to believe Henrik's accusation against Reyhan, Louis' attempt to help Vicky is interrupted when his grandmother is brought in, and Kian has to prove he is clean before he can operate.
Dominic confronts Max with his legal team before treating another stoma patient, Louis breaks the rules to help Vicky again and Kian ends up in a compromising position covering for Andrei.
Josh and Jeong-Soo find out that Louis is the hospital thief, Dominic tries to get Ange to join Sacha in operating on him, and Lucky realises Kian has been fooling her.
Henrik encounters Reyhan again when he is brought onto Darwin with a reopened wound, Sacha smuggles Dominic onto Keller as an excuse to do the stoma reversal and Fletch meets the new director of finance.
Henrik accepts the CEO position as the police launch an investigation into Reyhan's death, Dominic's conscience is pricked by two nurses' IVF troubles and Kian smuggles Andrei home.
Donna organises a nurses' protest as Dominic takes a turn for the worse, Andrei asks Lucky for help with Kian and Jeong-Soo realises a patient is in an abusive relationship.
With the hospital swamped with casualties from a school bus crash, Henrik is haunted while dealing with a pupil from his old school, Kian is too busy in theatre to help Andrei and Dominic advises Jeong-Soo on treating the bus driver.
Max meets an old flame who's now an oncologist while treating a patient with breast implants, Kian looks for Andrei and helps a man with chronic pain, and Dominic uses a colostomy patient and Sacha in a scheme to become consultant.
Kian and Fletch clash when Andrei and Evie are stabbed, Josh investigates unusual symptoms while trying to save his relationship with Ange, and Jeong-Soo is left with a patient while Sacha and Dominic interview for clinical lead.
Kian is rushed into theatre after his overdose, leaving Jeong-Soo guilty about his role in things, while Ange and Josh discover a further problem with Troy and Zoe.
Lucky and Chloe clash over a cancer patient's right to confidentiality while dealing with Kian's death, Dominic and a locum treat a patient with an eating disorder and Josh, Kylie and Louis adjust to their living arrangements.
As the hospital deal with the CQC inspection Henrik requested, a patient with a bite mark on Keller turns out to be a client of Jeni's, and Ange and Josh's relationship comes into focus when they treat his mother for MS symptoms.
Max tries to help Abs when he turns up looking for Henrik, who is in the basement. Ange and Josh deal with her pregnancy and a long-term cancer patient, while Dominic juggles a visit by Carole and a patient showing signs of domestic abuse.
Dominic learns of Carole's dementia after inviting her to the fundraiser, Josh's behaviour with Delroy assures Ange he will make a good father and Max convinces Henrik to talk to Abs.
The new director of improvement bring in new staff: Darwin clinical leader Eli Ebrahimi hits trouble with a stent research patient while nurse Madge Britton advises Kylie over being groped by a patient. Jeong-Soo helps Dominic with Carole.
Eli hits a snag with Mohammed's operation as Jac tries to get Max to use Carole as a trial patient; Delroy matchmakes between Kylie and Louis as his condition worsens; and Mia attracts the attention of Jeni while on work experience.
Eli and Chloe identify a new trial patient but hit a problem, Jac and Henrik clash when she closes AAU down just as Carole needs an urgent splenectomy, and Jeni manipulates Evie into continuing to take Mia to parties.
Dominic refuses to let Carole be used in Jac's trial when another patient dies, Evie's attempts to break free of Jeni falter when Fletch puts Rich in hospital, and Kylie tries to help a Crohn's patient make his school prom.
Chloe and the AAU staff are uncomfortable with treating Cameron, Evie tries to cover things up when Mia arrives drunk, and Dominic and Jeong-Soo take Carole on a pretend trip.
Henrik and Chloe worry that Cameron is still in the hospital, Jac debates the ethics of operating on Carole, and Evie and Jeni worry when a girl they know is brought in after a police raid.
Cameron deals with Bernie's return aware that the bomb he planted will soon go off, Ange is taken into theatre for a blood transfusion and Lucky continues her investigation as the Keller staff prepare to revive Rich.
Henrik is trapped under rubble in a corridor, Lucky lies unconscious in Jeni's office, Chloe and Josh have to deliver Ange's babies, and Bernie tries to get Cameron out of the collapsing AAU.
Fletch and Donna get closer to the truth about Jeni when Mia comes in with stomach pains, Jac treats a victim of the bomb blast and has to address her own medical problems, and Ange and Josh deal with being new parents.
Fletch and Donna wait for the police to take action against Jeni, Eli is bothered by a visit from his wife wanting to discuss IVF treatment and Elaine raises the tension for Ange and Josh.
Jac tries to charm a visiting doctor into authorising proton beam therapy, Donna struggles with the best way to handle Mia, and Lucky comes round but has spinal damage.
Josh is stressed juggling the twins, an important meeting and a compulsive eater, Lucky's recovery is hampered by a mysterious nurse and Henrik is accosted by Russell Faber, an old acquaintance who wants him to mentor someone.
Josh struggles to cope with both the twins and a patient whose operation has been delayed, Oliver's attempt to convince Henrik he can be retrained is hampered by a graffiti artist and Max enlists Kylie's help with Lucky's depression.
Josh's bulimia resurfaces as he tries to help a woman he thinks is being abused by her daughter, Lucky tricks Kylie into giving her an overdose and Henrik and Russell get locked in a store room.
Josh is stressed further looking after a terminally ill climate activist boy, having to operate on Russell's daughter causes problems for both Oliver and Ange, and Jeong-Soo looks after an elderly woman who insists she's fine.
Eli and Josh prepare to operate on Sammy as Amelia seeks help from Jac, Oliver's treatment of an appendicitis patient sees him clash with an old flame and Doreen tries to help Jeong-Soo celebrate his F2 promotion.
Lucky is brought back in with an infection, Oliver and Josh deal with an influx of patients from a fire at a care home, and Jac begins her proton beam therapy.
Oliver has a breakdown in theatre and injures Henrik, Josh tries to get consent from a patient with a fear of doctors and Max feels Dominic has jumped to conclusion with a diagnosis.
Josh attending a therapy session and Eli learning Amelia is pregnant affect their treatment of a man cared for by his teenage daughter, Henrik and Russell make up while treating a drunken patient, and Dominic has to accept Carole is dying.
Dominic and Sacha take Carole out for a last trip, Russell and Oliver realise there may be a treatment for Sammy and Eli discovers Amelia intends to continue with the pregnancy.
Henrik and the team prepare to operate on Sammy, Eli and Amelia learn they've lost their baby as a pregnant woman is treated for fluid round the heart, and Ange tries to support grieving Dominic.
Jac is determined to make a complex operation a success on the day of a review meeting, Russ tries to find a new recipient after a liver transplant patients dies and Kylie bonds with a young woman who was mugged for her bike.
Jac is rushed into surgery after collapsing again during her failed presentation, Dominic takes his issues out on Alan and Fletch is torn between his loyalty to the staff and the management.
Nicky is distracted from treating a social media star by the news Jac is terminal, an operation on Flo gives Dominic and Sacha an idea to stop infections on stoma patients, and Fletch debates the job offer while helping a father and son.
Fletch is determined to get Harry his operation but attempts to transfer him end in disaster, Henrik is in a quandary after finding out Billie is pregnant and Sacha and Dominic struggle to work together on their research project.
Nicky gets pushed out of her comfort zone treating the daughter of one of Cameron's victims, Donna feels taken for granted after Jason is brought in as a patient, and Max schemes to get Josh involved in his and Ange's wedding plans.
Serena and Bernie return to look after Jason, Jac's expanded HDU scheme sees her determined to get an old acquaintance an operation, and an injury to Kylie while chasing a patient is the final straw for Donna.
Max deals with both a dismissive haematoma patient and Forbes' dismissive attitude to Billie being in pain, Josh's demons resurface when Claudia is brought in with a ruptured oesophagus and Eli is worried by Amelia's plans to adopt Juliet.
An anthrax threat leaves Jac and Nicky trapped in theatre and Henrik having to deliver Billie's baby in the conference room, while Ange begins to realise who the mole is.
Madge is suspended for whistleblowing but then collapses with internal bleeding, an encounter with a constipated patient on the waiting list leads to Dominic job seeking elsewhere and Russ feels guilty for not noticing Billie was pregnant.
With the hospital out of special measures, Jac admits she's dying. Regina tries to get dirt from Madge, Josh and Jeong-Soo debate the junior doctor award as they treat Lexi, and Billie wants to move to Leeds and Russ stay with Henrik.
Fletch summons Elliot back in a last ditch attempt to save Jac, while Jac accompanies Kylie to investigate Madge's home life. Donna asks for her job back after helping Jeong-Soo save Lexy from a tension pneumothorax.
Jac prepares for her surgery. Josh has an awkward encounter with Claudia's mother before he, Ange and Dominic treat a homeless Ken Davies. Lexy has a kidney match but Jeong-Soo finds a complication.
Time is running out for Jac and she makes a fateful choice. Dominic is determined to help Ken as he remains left out with Ange and Josh. Lexy gives Henrik food for thought.