After Nell and Brad enter the hotel the first time, she removes her red gloves while talking, but then a bit further in the conversation she still has her glove on.
In the Act I it was shown aircraft landing for the 6 sec at Wisconsin Regional Airport. Nell arrived in it. However, the aircraft shown is Aeroflot Airbus A320. You can easily recognize it as every Aeroflot aircraft has a blue painted fin with a Russian flag. International airlines don't fly on regional flights, and Aeroflot had flights between Moscow and NYC/LA/DC/Miami only.
A Wisconsin radio station call letters would start with W not K.
There are no mountains in Wisconsin.
As Nell presents Hayley with a scrapbook after the birth of her baby, she opens the first page to reveal the title "Baby's First Scrapook" (the letter "b" has been left off) before showing her further pages.
In the ice rink scene there is a multistory office building in the background. Pretty unusual for small town of 1,171.
Nell and Brad arrive at Springdale Inn in the evening. It was snowing. They were met by Emmett. However, snow is clearly digital (not even faux) as there are no snowflakes on any actor, car, and sidewalk.
The same thing happened again at the end of movie.
Brad would not leave the hotel without taking his iPad.