Lillian tells Lena about a business partner of Lex's named Bruno Mannheim, who was an enemy of Superman in the comics. He was also mentioned on Arrow (2012) in season six's "Docket No. 11-19-41-73 (2018)".
According to the showrunners, Nia is intended to be an ancestor of Nura Nal aka Dream Girl.
This episode features the first television appearance of a transgender superhero.
At 13:30 when Agent Liberty states "Let him who desires peace, prepare for war" he is quoting the old Latin adage "Si vis pacem, para bellum".