When Diane is talking to her two daughters in Scottsdale while eating a slice of pizza, the amount of pizza on the plate keeps changing between shots although she is not eating it.
When Diane meets Mitchell meet in the plane and she sits next to him and they talk, her hair changes a couple of times between shots (mostly normal but twice behind her ear).
When the ladies are discussing the book at the emergency book club meeting, the amount of wine in their glasses changes between takes. Vivian holding a glass also changes between camera angles.
None of the crew members are wearing any sort of company or Airport ID, which is required to on their person above the waist and visible. This is usually done in the form of those IDs in a holder on a lanyard around their neck.
When Sharon replies to George, she decides to erase the last sentence. She hits the Delete button on the keyboard but the cursor erases left which is what the Backspace key does.
When Mitchell opens the door to the flight deck, there are all sorts of red and blue lights visible. There are very few blue lights in a cockpit, and almost no red lights except in some severe abnormal situations, such as perhaps the loss of an engine.
On the flight from Arizona, Diane is paged by seat 17B. Her seat is on the right, meaning it would be at least seat letter "D".
The cockpit door does not have a peephole up around eye level which is required on all US aircraft to be able to visually verify the status of the cabin and the Identification of persons for purposes of cockpit access in flight.
When Sharon is accidentally taking photographs of herself for her online dating profile, she holds her glasses upside down up to her face so she can see - however the photograph taken, the glasses are the correct way up.
The bottles and books in the bar behind the photo of the ladies from 40 years ago and the modern day photo are exactly the same.
The aircraft that is shown when Diane is flying back from Arizona is a CGI effect and not a real aircraft. This is evident by the engines being located two-thirds of the way out on the wing (instead of about 25%), and the windows being very tiny as if this aircraft had two levels, which is does not.
The CGI aircraft has no registration, or N-Number, visible on the aircraft.
When Diane is being paged on the airplane, the flight attendant is saying seat 17D. When the overhead compartments are shown, Diane's says 7, not 17.
When Mitchell walks out of the cockpit while acting as Captain, he has several days' beard growth. Pilots are not allowed to have facial hair except for a mustache that does not exceed the corners of their mouth. This is due to the tight-seal requirements while using a rapid-donning oxygen mask in the event of the loss of pressurization in the cabin. Any sort of a beard prevents a tight seal of the mask and, thus, is not allowed.
Bruce fails to kickstart his Honda CB750 motorcycle, apparently unaware that it has an electric pushbutton starter.
When Mitchell steps out of the cockpit to talk to Diane, he commits several violations of the Code of Federal Regulations. Since shortly after 9/11 there has a requirement to follow a security protocol which includes verifying that there is no one besides the crew near the door and blocking the aisle in some manner. In this case, Mitchell simply steps out into the cabin. When he returns to the flight deck, he knocks on the door and they immediately open it for him without any sort of verification. To make matters worse, the flight attendant walks away leaving no one there to block the aisle as he re-enters the cockpit. Additionally, a flight crewmember is only allowed to leave his seat for operational or physiological reasons, neither of which is the case here.