When Sophie gets out of her bindings, she is barefoot. As she escapes the doctor's house, running down the stairs and to his car, she is wearing shoes.
While in the hospital, the shadows of the Venetian blinds are on the girl facing forward but not on the side shots.
Though Eric Roberts, Jr.'s character is supposed to be a super-surgeon, and is shown preparing for an operation as well as rubbing ointment onto his patient's chest, at no time is he seen wearing medical gloves.
Cardiologists do not do surgery, other than implanting pacemakers or AICDs. There are usually two sides to every specialty, the medical side and the surgical side. For example, nephrology is medical and urology is surgical, but both involve kidneys, ureters and bladders. Cardiologists are medical and deal with the initial diagnosis, medications, risk factors, long term care of heart patients. Referrals are made to cardiac surgeons for surgical procedures. As a cardiologist, Dr. Beck would never do the surgery in this movie.
Car window glass does not shatter into shards like it did when it was hit with the tire iron. It fragments into tiny pieces.
Possible production mistake. The camera shows a close up of soccer trophies. One trophy character has a broken arm. Later, the trophies are hit with a basketball. It gives the impression that the earlier broken arm was filmed after another take of the basketball scene.