Puffless is a great Simpsons episode with a well written storyline and loads of very funny scenes. It's an enjoyable episode that nods back to several older seasons, bringing back Marge's mother, Patty and Selma's pet Jub-Jub, and even a Simpsons Movie reference which fans will be very pleased with. The weakest part of the episode was actually the main storyline, while a plot of Patty and Selma giving up smoking had potential, it simply didn't work out as well as it could have, the characters are too one-note to be able to hold the episode in lead roles, the main reason episodes like A Fish Called Selma or There's Something About Marrying worked is because there were several other characters involved, but just the two of them isn't enough, also the plot is poorly developed and has no resolution. Thankfully, this episode is saved by an outstanding side story that is clever and unique, as we see Maggie befriend a group of animals, eventually heading off on an adventure to save a possum, it's very fun and superbly animated, I liked seeing the show try something new and I'm perfectly fine with more side stories like this one, especially if they steal focus from a mediocre plot. Puffless easily could have been a mundane episode, but because of Maggie's triumphant side story it is great fun.
Patty and Selma decide to give up smoking, meanwhile, Maggie befriends a group of animals.