This episode is named after the I Love Lucy episode "Lucy is Enceinte" (premiered in December of 1952) in which Lucy finds out she's pregnant. The word "pregnant" was deemed inappropriate for television in the '50's, hence the French word used in title.
The scene in the bar with the dancing frog and watching chimpanzees refers to The Accused with Jodie Foster.
This is the last Family Guy episode to air on Adult Swim.