The future news article read by Barry and his team indicates that the fight between the Flash and the Reverse Flash is witnessed by the Atom, Hawkgirl, and "Starling City's Green Arrow."
The April 25, 2024 edition of the Central City Picture News mentions that Joe West is the Central City Police Chief.
The eye protection that Barry wears in S.T.A.R. Labs is the same eye gear that Captain Cold wears in the comics.
When Barry and the others find Wells' secret room, Gideon states that Barry is a founding member of an organization, but Barry interrupts. This was a nod to the Flash of DC Comics being a founding member of the superhero team Justice League of America.
This episode features flashbacks to when Barry was in a coma.