A copy-cat-killer who goes by the name The Trickster starts setting off bombs in Central City. In order to stop the villain, Barry and Joe meet with the original Trickster, a criminal mastermind named James Jesse, who has been imprisoned for twenty years. Things quickly go from bad to worse when the Tricksters unite and take Henry Allen prisoner. Meanwhile, Iris asks Eddie to investigate a missing person, and flashbacks show how Harrison Wells came up with the name for S.T.A.R. Labs.