Seth is seen extending his Tattoo into his neck, just like the Tattoo George Clooney had in the original movie.
At 5:55 the video clip is from 1959's "The Giant Gila Monster".
Danny Trejo plays The Regulator in 7 out of 10 of the episode of season 2. Danny Trejo stared in the 3 From Dusk till Dawn Movies. Danny Trejo is the only actor to have stared in every From Dusk till Dawn production.
At 17 minutes Richie references Lou Ferrigno, the Hulk in the original TV eponymous series.