- History of Everything(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Series theme song played during the opening titles]
- If I Didn't Have You (Bernadette's Song)(uncredited)Written by Garfunkel & OatesPerformed by Simon Helberg with Jim Parsons, Mayim Bialik, Johnny Galecki, Kaley Cuoco & Kunal Nayyar[Howard and his friends sing the song to Bernadette while she's in quarantine in the hospital]
- History of Everything (Instrumental version)(uncredited)Written by Barenaked LadiesPerformed by Barenaked Ladies[Instrumental version of series theme song played over the closing credits]
- If I Didn't Have You (Bernadette's Song)Written by Riki Lindhome and Kate Micucci
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![Johnny Galecki, Simon Helberg, Jim Parsons, and Kunal Nayyar in The Big Bang Theory (2007)](https://m.media-amazon.com/images/M/MV5BMzg0Mjg5Mzc5OV5BMl5BanBnXkFtZTgwOTE4NjQ0MDE@._V1_QL75_UY133_CR47,0,90,133_.jpg)