Futurama (1999) has ended a year and 2 months before this episode aired (September 2013). This is the last episode of any series to feature the Futurama cast until the Hulu reboot of Futurama in 2023.
When Homer is walking with Fry, Leela and Bender back to his house, they walk past Panucci's Pizza, the pizza restaurant Fry worked at before he got frozen in 1999. Fry's dog Seymour, who perks up and looks around thinking he saw something, is also shown still waiting outside.
Broadcast 25 years after "The Simpsons" was first broadcast in 1989 and 15 years after Futurama (1999) was first broadcast in 1999.
In the last scene Lrrr says "Perhaps the one of you that is female should talk to her." Shortly after, both Kang and Kodos go to talk to Ndnd. Kang and Kodos were established as sisters during Treehouse '96.
Despite being the central character of the series, Fry has only four lines. Zoidberg, Amy, Hermes, and Scruffy each have only one line. Most of the bulk of the dialogue belongs to Bender, Leela and Professor Farnsworth while some don't have dialogue at all.