Work on the story began in Spring 2020, following the release of Resident Evil 3.
This marks the first time all the protagonists have worked together.
Marks Jill Valentine's first canonical appearance in the Resident Evil franchise since Resident Evil 5 (2009).
For the first time ever, the movie features three of the four survivors of "The Mansion Incident" which took place in Resident Evil (2002) together: Chris Redfield, Jill Valentine, and Rebecca Chambers.
The writers confirmed that Jill ages slower thanks to the experimentation Wesker did on her. Which is why they use the model from the Resident Evil 3 reboot.