Jeff Davis (series creator) said that when Orny Adams (Coach) nailed the line "The bigger they are . . . the . . . bigger . . . they are" on his first take, he knew he fully understood his character. Orny Adams revealed in the nine year reunion that he hadn't understood the line at all and had followed a friend's advice to just take a shot at saying it how he thought it might be meant and get notes from the director if it was wrong.
Derek plays with and deflates a basketball in the beginning of the pool scene. He played basketball when he was in high school, as revealed in season three, and Scott played basketball in the original movie.
The Beavers (the mascot for the opposing lacrosse team) is the mascot for the school in the original Teen Wolf movie.
The Abomination's jersey number is 42, the same as Scott's in the original Teen Wolf movies.