- Rodrigo Borgia: [Shocked to see Ursula on the other side of the confessional] My eyes... !
- Rodrigo Borgia: You can believe them, Cardinal. I ask to confess in person to you that I must confess I have nothing to confess.
- Duke Ludovico Sforza: [Questioning his imprisoned nephew] What do you hunger for most?
- Gian Galaezzo: Freedom... and pheasant.
- Giulia Farnese: [Hearing that Rodrigo plans to arrange a marriage for 13 year old son Gioffri] Are you ever going to stop?
- Rodrigo Borgia: Never!
- Giulia Farnese: You are going to ensnare the whole of Europe... in your progeny.
- Rodrigo Borgia: What else are families for?
- Vanozza Cattaneo: You could leave the church and displease your father if you dare.
- Cesare Borgia: I fear nothing, Mother.
- Rodrigo Borgia: We have merged our fortunes with the Sforza name... the consequence of that trust being betrayed would be most severe.
- Cardinal Ascanio Sforza: Do you speak to me as Vice Chancellor, Your Holiness?
- Rodrigo Borgia: [Soberly] No, as a Sforza!