Episode dated 4 March 2021
- Episode aired Mar 4, 2021
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Divya Chadha Manek
- Self - Clinical Trials Lead, UK Vaccine Taskforce
- (as Dr Divya Chadha Manek)
Arlene Foster
- Self - First Minister of Northern Ireland
- (as Arlene Foster MLA)
Matt Hancock
- Self - Health Secretary
- (as Matt Hancock MP)
Boris Johnson
- Self - Prime Minister of the United Kingdom
- (as Boris Johnson MP)
Prince Harry
- Self
- (archive footage)
Keir Starmer
- Self - Labour Leader
- (as Sir Keir Starmer MP)
Nicola Sturgeon
- Self - First Minister of Scotland
- (as Nicola Sturgeon MSP)
Prince Philip
- Self
- (archive footage)
- (uncredited)
Oprah Winfrey
- Self
- (archive footage)
- (uncredited)
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