When the pilot and copilot are discussing Tom Hanks the copilots seat belt is being worn when the shot is of the back of him and not worn when the shot is showing his front.
This might be on purpose by the makers but the cockpit isn't A380 and the Captain should have 4 bars on his shoulder. As this is a bit of a wacky movie it may not be authentic for that reason so is just observational .
Around the 1 hour and 23 minute mark, an Italian character retrieves a Scorpion MP submachine gun from his black rucksack carry-on luggage. His companion then pulls a Colt M1911 pistol from his own carry-on. There is no explanation provided as to how either weapon made it through airport security.
While in the hold, Lucas Reyes drinks a vial of adrenaline to give himself heightened abilities. Adrenaline is a protein-based hormone that would be broken down by digestive enzymes in the stomach and intestines before it could enter the bloodstream intact. The acidic environment of the stomach would denature and inactivate the hormone.