This episode features the actual Roman and Virgil from
Sanders Sides (2016). Other episodes usually featured the Prince Guy and the Anxiety Guy, the original characters from Sanders Shorts (the Prince Guy would eventually inspire Roman and the Anxiety Guy was inspired on Virgil). In this case it is known they are the real Roman and Virgil from Sanders Sides because they wear the season 2 Sanders Sides outfits. The Prince Guy and the Anxiety Guy would have worn the season 1 outfits, the ones they've always worn in Sanders Shorts.