Dr. Cox treats a patient with Down Syndrome and John C. McGinley is still wearing his Down Syndrome awareness bracelet for his own son.
The song Ted (Sam Lloyd) and Gooch (Kate Micucci) sing on the couch is an original song from her (Micucci) comedy band Garfunkle and Oates.
Doctor Cox has a red Swingline stapler in his office. John C. McGinley was in the movie Office Space (1999), which made this stapler famous.
Jack staples his clothes to the wall over a stick figure child and tells his parents "I finally have a brother!" Andrew Miller - Jack - has a twin brother named Jakob.