This is the last Detective Conan movie to use hand-colored cells (traditional animation).
This is the first film where Conan's gadgets are primarily absent, as in the game they are useless, so he has no realistic application for them aside from inside the game. The next movie where Conan is unable to fully utilize them is Detective Conan: The Fist of Blue Sapphire (2019), though he gains them back later on.
Sherlock Holmes and Dr. Watson are said to be away on business at Dartmoor in reference to The Hound of the Baskervilles case, however this case did not take place until a year later in 1889.
This is the only film where either of Shinichi's parents are actually directly involved with the story line. Yusaku cameos in Detective Conan: The Fourteenth Target (1998) and the two appear in the introduction sequences for Detective Conan: Countdown to Heaven (2001) and Detective Conan: Crossroad in the Ancient Capital (2003), but not in the films themselves aside from that, though Yusaku is mentioned later on in Detective Conan: Countdown to Heaven (2001).
The date in London is declared to be September 30, 1888 which is a Sunday, yet Moriarty says that the following day is to be Sunday.