- Two pairs of lovers on a Hawaiian vacation discover that psychopaths are stalking and murdering tourists on the islands.
- For their honeymoon, newlyweds Cliff and Cydney head to the tropical islands of Hawaii. While journeying through the paradisaical countryside the couple encounters Kale and Cleo, two disgruntled hitchhikers and Nick and Gina, two wild but well-meaning spirits who help guide them through the lush jungles. The picturesque waterfalls and scenic mountainsides quickly give way to terror when Cliff and Cydney learn of a grisly murder that occurred nearby and realize that they're being followed by chance acquaintances that suspiciously fit the description of the killers.—The Massie Twins
- On Hawaiian honeymoon, Hollywood Screenwriter Cliff Anderson and his bride Cydney go from Honolulu to pristine island Kaua'i for an adventurous hike in the nature reserve, for which Cliff forgets his permit in the supply store. Reluctance to give macho Kale and his girl Cleo a ride creates tension that remains when they meet on the trail, with a third couple taking the lead: studly special forces Irak veteran Nick, who even hunts wild goats, and his equally exhibitionist steady girl Gina. Receiving the news that a serial killer who murdered a couple on Oahu probably passed to the island, as they did, starts the couples mistrusting each-other. Furthermore they seem to be followed by mystery stalkers, as turns out of two kinds. After the battle of whit, a bloody struggle for survival is inevitable: the killer is among them and strikes, despite a police helicopter searching for him.—KGF Vissers
- Newlywed Hollywood Screenwriter Cliff Anderson and his wife, Cydney, head off to Hawaii for their honey-moon. After obtaining permits they drive a rented car and encounter hostile hitch-hikers, Cleo and Kale. They subsequently come to find out that police have discovered a brutally murdered couple with their teeth and nails removed. Cliff and Cydney then encounter war-vet Nick and his girlfriend, Gina, and together the four trek their way towards a popular beach. It will not take them long to realize that both Nick and Gina are a little odd, but before they could decide to separate from them, they find themselves confronted by Kale and Cleo, as well as unknown stalkers.—rAjOo (gunwanti@hotmail.com)
- A young mild-mannered American couple, Cliff (Steve Zahn) and Cydney (Milla Jovovich) are celebrating their honeymoon by hiking to a remote beach in Hawaii. Cliff went to film school and is a screenplay writer. Cydney notices that Cliff has an unexplained scar just below his chin. Cydney records their hike in Hawaii. Cliff and Cydney are on the Kalalau trail which ends in a pristine dead-end beach in one corner of the Island. The hike takes 2 days on foot and is 11.5 miles each way. Cliff and Cydney drive to the entrance of the trail and on the way, they come across 2 hitch hikers Kale and Cleo. Cliff makes an excuse and refuses to give them a ride. Cleo is super friendly and shows Cydney her wedding pictures, convincing her to drop them to their destination. But now, Kale angrily asks Cleo to get out of the jeep and he refuses to accept the ride.
The couple comes across Nick (Timothy Olyphant) a solo hiker, who saves Cydney's life when she slips crossing a narrow ledge. The trio approach a group of frightened female hikers discussing a double murder in Honolulu of another newlywed couple on the island, with the victims having their teeth pulled out and fingertips removed, Cydney and Cliff discuss whether they should turn back. The authorities are looking for 2 people, a man and a woman.
The couple decide to continue hiking with Nick, who claims to be an Iraq War veteran and subsequently meet up with his girlfriend, Gina (Kiele Sanchez). Nick indicates that he was with a special operations group who attacked Saddam's Palace. He says that Saddam had a lock box inside his bathroom, where he stored his collection of Iran Man and Sub-Mariner comics. Nick was also injured on the back of his head by shrapnel from the anti-personnel mines and has a titanium plate inserted to rebuild his skull. Nick says that there are no nerve ending in the brain, so brain injuries cause no pain.
Cliff suspects that the couple of hitchhikers that he and Cydney had earlier turned down for a ride Cleo (Marley Shelton) and Kale (Chris Hemsworth) and run into on the trail might be dangerous. Kale is mighty angry at Cliff as he believes that Cliff looks at him and Cleo as some desperadoes because of the way they look. Cliff checks their bags after discovering that his and Cydney's permits are gone. Then, he, Cydney, Nick and Gina leave together. Nick suspects that Kale and Cleo are following them. Nick's aggressive and psychotic behavior makes him a prime suspect for the murders. Nick says that he is sharing all the gory details with Cliff, about his injuries in Iraq, so he can make his movie as realistic as possible by getting the details right. Cliff manages to get cell reception and looks at internet photos of the suspected killers, and it looks like Nick and Gina.
Nick and Cliff split up to search for Kale and Cleo. Nick reveals that he knows that Cliff and Cydney believe that Nick and Gina are the killers. Cliff runs into a guide he and Cydney had met before setting off on the hike, who gives him the permits they had left behind. He and Nick return to the campsite, with Nick bringing a goat he had killed. Gina proceeds to expertly gut and butcher the goat, saying she learned how by working in the meat department of a grocery store. The following day, Kale and Cleo are arrested by the police. A container full of pulled teeth is found in their bag. Cliff, Cydney, Nick and Gina head to the beach, where Nick and Cliff decide to go see a marine cave via kayaks.
As Gina idly looks through the photos on Cydney and Cliff's video camera, she is horrified to realize that they are not who they say they are. Gina sets off after Nick and Cliff with Cydney chasing after Gina. Flashbacks then reveal that Cliff (who turns out to be Rocky) and Cydney are a drug addicted sociopath couple who murdered the newlyweds in Honolulu. They kill people and take their identities in order to, as Rocky (the most psychotic and deluded) puts it, live a hundred different lives and achieve a kind of immortality. It is also revealed that "Cliff" planted the teeth in Kale and Cleo's bag to frame them.
In the cave, Rocky shoots Nick just as Gina arrives, having run along the cliffs. Rocky shoots at her, but misses. Cydney sneaks up on Gina and attacks her. Gina is stabbed in the leg but manages to push Cydney off the ledge into the water.
Gina fortuitously receives a call on her cell phone from a phone company representative. She begs him to call the police. She then spots Cydney below in the kayak just as Rocky pops up over the cliff ledge to grab her feet. Gina stabs him in the hand with Cydney's knife and flees. While Rocky chases her and Cydney kayaks ashore to intercept the police, Nick, saved by the titanium plate in his head, wakes up. Gina, in turn, runs into a group of men searching for their stolen kayaks, who tell her she is safe now. Rocky tries to convince the men that Gina is whacked out on drugs, but when one of them, who happens to be an EMT (Emergency Medical Technician), notices his enlarged pupils, he ends up killing all of them as Gina runs toward the beach.
At this point, Nick arrives and fights with Rocky, eventually getting the upper hand. At that point, the police arrive by helicopter with a rifle aimed at Nick. They ask for confirmation from Cydney (Cidney makes the police believe that she was the one who made the phone call), accompanying them in the helicopter, that Nick is the killer, and she pauses. Gina pulls Nick away from Rocky just in time to save him from the police sharpshooter. Cydney then tells the police that Rocky is the killer. She does that as even she afraid of the psychotic rage within Rocky & she sees this as a perfect way to be rid of him. Rocky is shot dead as he reaches for his gun.
Later, a medical helicopter comes and takes Nick and Gina. Nick proposes to her on the helicopter and admits that he had bought the ring on eBay. She happily accepts and they agree: "No honeymoon."
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