Sharon Osbourne got her role by bidding on it at a charity auction for the Trevor Project in December, 2003.
Karen and Jack tell Bebe that they "didn't care for season 8" of Frasier. Season 8 is generally ranked the worst season by critics and fans alike.
Megan Mullally appeared on an episode of Frasier (Four for the Seasaw)
Karen (Megan Mullally) tells Bebe Neuwirth (guest staring as herself) to talk like Lilith (her character on Fraser) because the don't like the way her real voice sounds. Bebe replies I will if you will. Megan Mallally speaks in a higher range for Karen than her real voice.
The title references Sex and the City (1998). Guest-performer Bobby Cannavale appeared in Easy Come, Easy Go (2000).