Steven Spielberg provides the voice for the white rabbit auditioning for Buster and Babs at the start of the episode. This character is a takeoff on Roger Rabbit, star of a film produced by Spielberg.
Real life music trio, the Roches, guest star as characters based on themselves but drawn as, of course, cockroaches.
In an in-joke for fans of the Roches, Terre and Suzzie are surprised when Maggie begins yelling at Hamton. This is because, in their live performances, Maggie hardly ever speaks, leaving the stage chatter to Terre and Suzzie.
Duck Twacy was a classic Daffy Duck cartoon based on the hugely popular comic character Dick Tracy. His line "honest to Warren Beatty" is a reference to the movie from 1990 in which Beatty played Tracy.