The name of this episode may be an allusion to Robert A. Heinlein's 1958 novel Methuselah's Children, which was about a group of long-lived humans who hijack a generational starship to escape persecution on Earth.
It was on May 2, 2790 A.D. that Devon, Garth, and Rachel broke into Alpha Complex 3, according to the character initially known simply as "4", but later named "Jacob" by Rachel.
All of the names given to the children - Sarah, David, Jacob and Elizabeth - all come from the Old Testament of the Bible.