The episode centers around a fictional former Cheers (1982) writer named "Charles James". The character is named after the actual creators of "Cheers", Glen Charles, Les Charles, and James Burrows.
Was actually filmed in front of a live studio audience.
While normally a single camera show, this episode pays homage to classic sitcoms by adopting a four camera setup. Ironically, it went on to win an Emmy Award for Outstanding Multi-Camera Picture Editing.
The four cameras in the title refers to the typical multiple-camera setup in a sitcom setting, where usually four cameras will be set up to capture different angles of a scene at one go.
Sarah Chalke (Elliot Reid) is actually fluent in German (and French).