Gail Edwards (Tracy Knight) and Richard Stahl (Uncle Floyd) who appear in this episode, co-starred on the 1980s series "It's A Living" from 1985-1989.
Richard Stahl, who plays Uncle Floyd, also played Dr. Peter Green in S1E2.
The title is based on the MacDonald's Hamburgers ad slogan "Big Mac attack" that one gets when one is hungry.