The title is from the 1944 song "You're Nobody till Somebody Loves You" written by Russ Morgan, Larry Stock, and James Cavanaugh.
The role of George Utley was written with Jerry Van Dyke in mind, but ultimately he was not cast in the role.
The role of travel agent Betty Houser was played by Maggie Kemp, wife to series creator and executive producer Barry Kemp. This is the first of her two acting credits (the second was in an episode of the Barry Kemp-written miniseries Episode #1.6 (1986), which series also featured Jerry Van Dyke).
Jerry Van Dyke (Roy Herzog) went on to play Assistant Coach Luther Van Dam on Coach (1989), a long-running sitcom created and executive produced by Barry Kemp, who was also the creator and executive producer of Newhart.