First of four appearances of the time-traveling science fiction author H.G. Wells.
Lois and Clark travel back in time in pursuit of Tempus (Lane Davies), who is intent on destroying the infant Superman. The field where the Kryptonion spaceship carrying the infant landed is called Shuster's Field. Joe Shuster was one of the creators of Superman.
This episode takes place in 1995, on May 17, 1866 and on May 17, 1966.
The title is taken from Ken Steacy's four-part graphic novel series Tempus Fugitive, published by DC Comics in 1990-1991. The graphic novel was rendered in airbrush, a novel medium for comic books at the time, but is unrelated to the episode beyond the time travel aspect and the title.