When the detectives first meet the real estate broker Cary Stillman, he has finished eating his lunch, and is folding up a piece of aluminum foil, to reuse later. He folds it up 3 times, small, as he is talking, but when he places it into his drawer, it is only folded twice. large.
Both Dr. Rogers and Detective Briscoe describe a .380 slug as "small caliber". However .38 caliber bullets are known as "medium caliber". Anything below .30 caliber (such as a .22 LR or .223 Remington) is considered small caliber, .30 to .38 is medium caliber and any slug larger than .40 caliber (such as a .40 S&W, .44 Magnum or .45 Auto) are large caliber.