Jeff Franklin said that the scene that got Full House on the air was the scene where Uncle Jesse and Joey change Michelle's diaper.
In the pilot, Joey does a voice impression of Kermit the Frog to cheer baby Michelle up. Dave Coulier who plays Joey on the show was the voice of baby Animal on Muppet Babies, which also featured Kermit the Frog.
Debut for Mary Kate and Ashley Olson.
D.J. states that Kimmy Gibbler has three sisters, but later she only has a brother.
If you don't count the unaired Pilot, this is the first appearance of Alice Hirson as Claire Tanner.