The main guest stars were all regulars on various spy shows of the 1960s: Barbara Bain from Mission: Impossible (1966); Robert Culp from I Spy (1965); Patrick Macnee from The Avengers (1961); and Robert Vaughn from The Man from U.N.C.L.E. (1964). Out of all of the actors, only Barbara Bain played the same character from the original show.
Phil Morris, who plays "Jim Kesler," is the son of Greg Morris who played Barney Collier in the original Mission: Impossible series. Phil also starred in the 1988 reboot of the classic series, where he played Barney's son.
Jesse's father tells him to meet him at DelFloria's for dinner. In the Man From U.N.C.L.E. series, "DelFloria's" was the tailor shop that housed the secret entrance to U.N.C.L.E. headquarters.