When Tim Robbins directed his first feature film, Bob Roberts (1992), Helen Hunt appeared in a brief cameo as a television news reporter. When Hunt made her feature directorial debut with this film, Robbins returned the favor and appears briefly as one of the interviewees on the Bette Midler character's talk show.
Reunited real-life exes Helen Hunt and Matthew Broderick, who dated 20 years earlier when making Project X (1987).
The doctor who does April's ultrasound scans is played by the English author Salman Rushdie. He is famous for having a fatwa against him by Ayatollah Khomeini of Iran.
ThinkFilm and Canadian distributor TVA Films bought the U.S. and Canadian rights, respectively, for the film at the 2007 Toronto Internation Film Festival.