Louie's dad is named Andy in the cartoon, but in real life, Louie Anderson's father was named Louis.
Many scenes are true stories from Louie Anderson's past, such as the buying of the Xmas tree and dad saying that because the tree cost $35, it should dance.
The origin of a running gag in the series, in which Mrs. Stillman's Christmas lights are still up many months later, and she would repeatedly ask Andy when he'll help take them down.
Andy's car is based off a '59 Rambler Rebel.