Dean Cain's character is a scientist, and so is his wife, but at the end of his opening lecture, he comments that his wife scored higher on her GMATs than he. GMATs are the business school entrance exam, whereas a scientist must have taken the GREs.
In the beginning of the movie the word Antarctic is spelled "Antartic".
All of the inmates are supposed to be in what is going to be a maximum security prison and yet the weapons the get to fight the boa with are basic handguns and machine guns. Yet, if this really was a maximum security prison the weapons that would have would be stronger and definitely much more powerful.
The actors throughout the film wear to many thin clothes and realistically they wouldn't have been able to survive in Antarctica. They would have died from cold quickly and yet not one of them seems to be effected by it and even at the end when there right in the middle of it, they don't even shiver.
In the scene when Dean Cain's character crawled out of the hole that the charge explosion blew out the hole, you can see that some of the snow wobbles when Cain stumbles into it.
The boa in the film is very obviously Computer generated, and doesn't hold up even for its time, and it's clear that any of the shots with actors were done with computer effects and they have aged poorly.
The first time we see the Warden talking to Yuri, we see the Warden's reflection in the cell glass. At one point his lips continue to move for several seconds after he is done speaking.
The guard tells Yuri that he's "20 miles north of the south pole". This isn't an actual geographic location. Once you are standing on the south pole, you can walk 20 miles in any direction and you are going north.