The show was a combination of heroes from older Hanna-Barbera series and some brand new characters. Space Ghost and the Herculoids had their own respective series during the 1960's and has brand new adventures for this series. Astro came from The Jetsons. The Teen Force, Space Ace and the Space Mutts were created specifically for this series.
When the Herculoids had their own series, their home world was named Amzot. In this series, their homeworld was renamed Quasar.