This is the final appearance of Scrappy-Doo in the 20th century. His next appearance was in Scooby-Doo (2002).
Vanna Pira is based on Vanna White of Wheel of Fortune (1983) and Maila Nurmi of Vampira Returns (1956).
Dracula spends the movie pronouncing Shaggy's name as "Sha-Gee". Years later, Chapter 20 (2004) introduced a character modeled after Shaggy named Sha'a Gi, whose name is pronounced the same as how Drac did it.
Compared to Scooby-Doo Meets the Boo Brothers (1987) and Scooby-Doo and the Ghoul School (1988), which used hand-painted cel animation, this one was digitally colored in-house at Hanna-Barbera. At times, limitations of the early computer system really show. This and Yogi & the Invasion of the Space Bears (1988) (which came before this one) were the only two movies in the Hanna-Barbera Superstars 10 series to use digital ink-and-paint.