After the first fight, Proteus' shirt collar is ripped. When he follows Sinbad into the ship's cabin, his shirt is perfect again.
When Sinbad and Marina are sliding on the shield, it is strapped to Sinbad's back in the beginning. Throughout the rest, the straps are completely gone.
Throughout the movie, Sinbad's weapons change places, appear and disappear again.
When Sinbad used the harpoon to shoot himself to that rock, immediately he was on the rock, the rope tied around him disappeared.
When Eris was furious with Sinbad for returning to Syracuse, she swiped the beheading platform on which Sinbad had his head moments before and it fell off the cliff into the sea; but when Sinbad got the Book afterwards and held it up, the same platform could be seen behind him.
In the beginning it clearly showed that Eris pulled a thread from the world that is round. When Sinbad reached Tartarus, the "end" of the world indicated that earth is flat.
The movie is set between 733 BC and 212 BC. Yet, Sinbad and his crew know of Fiji. Fiji was not discovered by Westerners until 1643 AD.
The movie is set between 733 BC and 212 BC. Yet, one of Sinbad's sailors is is wearing glasses. The earliest precursor of this optical device was not invented until 1300 AD.
At the end of the movie when Sinbad is telling Marena that it is "very, very dangerous" his mouth movements do not match up with his words.