A chimp in a spaceship goes off course into the far edges of the universe. Aliens enhance his intelligence to make him Captain Simian, so he can defeat the evil Nebula, who wants to take over the universe.
The crew find a derelict ship, some crystals and an alien egg. The egg hatches with a quick-evolving alien that threatens the ship and crew. Splitzy uses the crystals to trap the alien and dump it into space.
The crew encounter an idyllic-looking, Earth-like planet run by a protege of Nebula, Rhesus 2, who has actually enslaved the planet. Captain Simian and his crew has to free them.
An unknown ship attacks the Avenger crew, kidnapping Gor and Spydor, who are forced into a fight ring. The Simians find them just in time to rescue them.
Giant alien bananas attach to the ship, capturing some of the crew and making clones of them that take over the ship. The captain has to find the home origins of the bananas in order to free his crew and ship.
Rhesus 2 steals gravitons that cause a rip in the fabric of the universe. Charlie helps an alien put the gravitons back to seal the rip and save the alien's world.
The Simians ride a meteor through a wormhole, finding an alien planet on the other side that the meteor is about to hit. They try to warn the inhabitants but can't communicate, so they have to save the alien planet themselves.
A psycho-neutron annihilator bomb destroys all life forms and can protect itself from being discovered. And Rhesus 2 has just put one on the Simian ship, forcing the monkeys to face their fears in order to disarm the bomb.
On a primitive planet, the Monkeys find two aliens undergoing a rite of passage. One alien befriends the monkeys, the other joins a group trying to capture the Monkeys. An intervention shows that things aren't what they seem.
A microscopic-size ship of alien pioneers is looking for a home, and they settle for Spydor's rear end. Simian and the others shrink down to find and convince the intruders to go elsewhere.
Damaged in battle, the Simian ship lands on the planet Maltese. So the crew follows the Orbitron's trail through a noir-world of alien gangsters and molls, where nothing is what it seems.
A powerful being calling himself the Glyph offers Simian the chance of destroying Nebula. The plan is to lure Rhesus 2 into a trap and get him to lead them to his master. But the crew soon discovers that their new ally has an agenda of his own.
The Space Monkeys need a few androids to help in defending the universe. When the crew searches for more advanced machines on Cyber 1, they find the planet is run by Matrix, who believes he has created a whole civilization of robots.
In the Caelin system, the primate ship is shot down and sinks into the pink ocean covering the planet. But the monkeys don't drown and now find they must stop the two warring factions on the planet before they destroy it.
Nebula has figured out how get his hands on the GLOP generator. The Space Monkeys rush to the scene, as does Mandrax, a mysterious mandrill with unimaginable powers. What will Mandrax do?
Nebula has the GLOP generator but needs one last part from the Primate Avenger. Attacked by the ganglia, the Space Monkeys are snared in Rhesus' energy net and about to be tortured. Will they be saved by their captain?
Capt Simian is lost on a world of illusion, and only a visit from the mysterious mandrill Mandrax can save him. Can he stop the madman Nebula from using the final component he needs to destroy the universe?