This was Gabriel Byrne's first American film. He later claimed that the experience had almost made him give up acting.
If the main theme and musical cues in the film sound familiar, it's because they often sound like 'variations on a theme' from "Arthur's Theme" by Christopher Cross.
Illeana Douglas's debut.
According to imnotastalker(dot)com: "In the 1987 comedy "Hello Again [1987]", the Fletcher-Sinclair Mansion portrays the home of Junior Lacey (Austin Pendleton), where Lucy Chadman (Shelley Long) and her sister, Zelda (Judith Ivey), go to ask for funding to start a day care center at the Knickerbocker Hospital." The mansion sits at the corner of 79th Street and 5th Avenue.
Final credited film appearances of actress Carrie Nye and casting director/actress Shirley Rich. Nye and Rich did however live on until 2006 and 2009 respectively.