Captain Grey Holden's (Darren McGavin) riverboat was named "Enterprise".
Burt Reynolds left the show in the middle of the first season because of behind-the-scenes disputes with Darren McGavin. He was replaced by Noah Beery Jr.. when the second season began.
Scenes showing the riverboat Enterprise paddling down the Mississippi River were miniature sets filmed in Hollywood.
Chip's dog, Andy Jackson, never received any screen credits.