Hale Hamilton's character Monroe is said to be a descendant of James Monroe and Benjamin Franklin. James Monroe had two daughters and no sons. Descendants, if any, would not have the surname Monroe.
In the opening credits Loretta Young's character is listed as "Madeline," but on her marriage license that can be seen at around the thirty minute mark (on the double decker bus) her name is written as "Madeleine" Walters.