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- A dangerously charming, intensely obsessive young man goes to extreme measures to insert himself into the lives of those he is transfixed by.
- The daily lives of healthcare professionals in a Pittsburgh hospital as they juggle personal crises, workplace politics, and the emotional toll of treating critically ill patients, revealing the resilience required in their noble calling.
- Follows a legacy Hollywood movie studio striving to survive in a world where it is increasingly difficult for art and business to live together.
- A Secret Service agent investigates the murder of a former president in a seemingly peaceful community.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- Aspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.
- Follows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- A scrappy, feisty, fiercely loyal Chicago family makes no apologies.
- Follows the titular superhero as he reconciles his heritage with his human upbringing. He is the embodiment of truth, justice and the human way in a world that views this as old-fashioned.
- Meet a child genius named Sheldon Cooper (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon, who is socially impaired.
- Georgie and Mandy navigate the challenges of adulthood, parenting, and marriage while raising their young family in Texas.
- Rue Bennett is a drug addict fresh from rehab, who's struggling to stay clean and make sense of her future. Her life changes drastically when she meets Jules Vaughn, a trans girl who recently moved to town following her parents' divorce.
- Follow-up to the comedy series Roseanne (1988), centering on the family members of the matriarch after her sudden death.
- When Earth becomes uninhabitable in the future, a farmer and ex-NASA pilot, Joseph Cooper, is tasked to pilot a spacecraft, along with a team of researchers, to find a new planet for humans.
- A famous "psychic" outs himself as a fake, and starts working as a consultant for the California Bureau of Investigation so he can find "Red John", the madman who killed his wife and daughter.
- A dramedy centering around the relationship between a thirtysomething single mother and her teen daughter living in Stars Hollow, Connecticut.
- A thief who steals corporate secrets through the use of dream-sharing technology is given the inverse task of planting an idea into the mind of a C.E.O., but his tragic past may doom the project and his team to disaster.
- Set almost 100 years after Captain Kirk's 5-year mission, a new generation of Starfleet officers sets off in the U.S.S. Enterprise-D on its own mission to go where no one has gone before.
- Lucifer Morningstar has decided he's had enough of being the dutiful servant in Hell and decides to spend some time on Earth to better understand humanity. He settles in Los Angeles - the City of Angels.
- An industrialist invites some experts to visit his theme park of cloned dinosaurs. After a power failure, the creatures run loose, putting everyone's lives, including his grandchildren's, in danger.
- A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- At the intersection of the near future and the reimagined past, waits a world in which every human appetite can be indulged without consequence.
- Two detectives, a rookie and a veteran, hunt a serial killer who uses the seven deadly sins as his motives.
- Telepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill Compton, a southern Louisiana gentleman and vampire.
- Inside the lives of staffers in the West Wing of the White House.