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- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- As Hollywood's Golden Age is winding down during the summer of 1969, television actor Rick Dalton and his stunt double Cliff Booth endeavor to achieve lasting success in Hollywood while meeting several colorful characters along the way.
- A dramatization of the life story of J. Robert Oppenheimer, the physicist who had a large hand in the development of the atomic bombs that brought an end to World War II.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- A young woman, destined to slay vampires, demons and other infernal creatures, deals with her life fighting evil, with the help of her friends.
- The continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- A thief who steals corporate secrets through the use of dream-sharing technology is given the inverse task of planting an idea into the mind of a C.E.O., but his tragic past may doom the project and his team to disaster.
- A close-knit group of housewives reside in Wisteria Lane. It may appear to be a seemingly perfect neighborhood but it hides many secrets, crimes, forbidden romances and domestic struggles.
- The lives and tragedies of the Braverman family tree.
- An industrialist invites some experts to visit his theme park of cloned dinosaurs. After a power failure, the creatures run loose, putting everyone's lives, including his grandchildren's, in danger.
- At the intersection of the near future and the reimagined past, waits a world in which every human appetite can be indulged without consequence.
- Professional writer and amateur sleuth Jessica Fletcher uses her intellect, charm, and persistence to get to the bottom of every crime she encounters.
- Rival 19th-century magicians engage in a bitter battle for trade secrets.
- The husband of a missing woman becomes the chief suspect in her disappearance.
- Blacksmith Will Turner teams up with eccentric pirate "Captain" Jack Sparrow to save Elizabeth Swann, the governor's daughter and his love, from Jack's former pirate allies, who are now undead.
- Marty McFly, a 17-year-old high school student, is accidentally sent 30 years into the past in a time-traveling DeLorean invented by his close friend, the maverick scientist Doc Brown.
- A comet is discovered to be on a collision course with Earth. As doomsday nears, the human race prepares for the worst.
- Harvard symbologist Robert Langdon works with a nuclear physicist to solve a murder and prevent a terrorist act against the Vatican during one of the significant events within the church.
- Los Angeles homicide detective, Lieutenant Columbo, uses his humble ways and ingenuous demeanor to root out even the most well-concealed crimes.
- In the 1980s, a determined criminal-minded Cuban immigrant becomes the biggest drug smuggler in Miami, and is eventually undone by his own drug addiction.
- Pulled to the far side of the galaxy, where the Federation is seventy-five years away at maximum warp speed, a Starfleet ship must cooperate with Maquis rebels to find a way home.
- An insurance salesman begins to suspect that his whole life is actually some sort of reality TV show.
- A group of Crime Scene Investigators work with the Las Vegas Police Department to solve crimes by using advanced scientific methods and technology.
- The life and adventures of the Ingalls family in the nineteenth century American Midwest.