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- A rugby player gets a broken leg in a match. He dies from a brain bleed. After investigating, it is revealed that his best friend punched him in the head and caused it. Janice finds Chrissy's name badge and confronts Alistaire and he weasels his way out of it. He gives her the necklace that he bought for Chrissy. Janice is pregnant.
- Jess tries to tell Ric about the baby. Rosie wakes up with no recollection of the fire and Mubbs pretends they are still a couple. Jess has a scan and realizes the baby is Zubin's.
- A mother sees Steve hugging her daughter, but when she asks her about it, she claims that Steve kissed her. Steve is charged with misconduct and suspended until an inquiry is held. Danny's first day as student nurse.
- Meyer has to operate on his mentor, but finds out that he himself has a debilitating illness. Julie's daughter becomes seriously ill and is admitted. One misbehaving boy in the children's ward is stealing Santa's chocolates.
- Julie begs Meyer to operate on her daughter Rosie, but he refuses as he needs time off due to his illness. A fireman comes in with smoke inhalation, only to find out he has lung cancer. Danny and Stan bring Santa to the hospital.
- Sandy wins 150,000 pounds in the lottery and leaves the money to Jess, Ric and Kelly and pays off Lisa's mortgage, and then goes to Australia to hook up with Danny. Owen asks Tricia to go on a vacation.
- Jess gets tested for a STD that she blames Sean for. Tricia tells her friend Maggie her Cancer results and Connie is angry that Tricia has no authority to do so. Connie berates Lisa about having no control over her staff.
- A crisis occurs when a power outage happens while Mubbs is operating. Kath pleads not guilty. Lisa takes it out on Danny. Ben goes off with another man at the Valentine's Day party.
- A jousting match goes horribly wrong when two rival accountants end up in Holby. Connie sends Wil back to cadaver training. Tricia thinks Carlos will end it, but he has a surprise for her. Jess ends it with Raza, then kisses Zubin.
- An autistic patient challenges Meyer to a chess game. If Meyer cannot beat him, the man won't have the life saving heart surgery.
- The woman that Nick saved from the crash is found to have drugs in her system, memory loss and bruising all over. The staff think it is date rape. Nick has surgery on his hand and is told he may never operate again.
- Terry left everything to Kath, and Lisa is suspicious. Owen's stag night. Mubbs finds out that Ed is the father of Chrissie's baby. Lisa calls the police on Kath after having a fight with Danny.
- Sean Thompson, Zubin's replacement starts today. Diane asks Owen to marry him. Connie and Will are getting on a lot better. Chrissie worries about a lump in her breast.
- Danny confronts Sean and he runs away. Chrissie's office is full of her belongings, courtesy of Owen. Owen catches Ed and Chrissie together in an embrace and goes wild. Ben breaks off with Tony.
- Ric agrees to take cash for doing a private surgery, but the patient's father threatens him, that if his son dies, he won't pay up. He also threatens to have him beaten up. Rosie insists to Mubbs that he should get a woman's medical records and he doesn't. The woman lies to him and endangers the baby.
- It's Jess's 21st birthday party and the gift Ric gives her is repossessed. The cause of the Kellar deaths is revealed, and Owen and Chrissie reunite.
- The canteen is not at full capacity and Will complains to the kitchen staff. The staff go on strike. Will refuses to apologize and Connie suspends him. Rosie has an emergency Cesarean but the baby does not make it and she dumps Mubbs.
- Kirsty goes behind Meyer's back and treats a dying patient with experimental drugs. Danny gets mugged in the parking lot. Barratt sings Karaoke at the staff party.
- Chrissy tells Sam that she will tell Alex that Sam spiked his drinks. Sam goes to Alex, and as she is about to tell him, he tells her he loves her. A man who was a bully at school, gets a bed next to a man who was his victim, with unfortunate results.
- Rosie tries to set Mubb's up on a date with disasterous results. Kelly, who wants Kath's job, sets her up to fail in an interview for a better job.
- New Year's day. Chrissie wakes up in Mubb's bed and tries to sneak out. The organ ambulance is stuck in traffic and the recipient dies waiting for it. There is a second patient waiting as well, so they give it to him, but he dies too. Tom blames the system and Zubin calms him down.
- Jess finds herself at the centre of a baby-shaking scare after she rushes Paris to hospital and bruises are found on his body, while Michael is blackmailed. UKTV PLAY description.
- Connie hires Mark to help when they are short of nurses, and Tricia is fuming mad. Jess finally tells Sean he is not the father of the baby. Lisa puts Donna in charge to show her how hard it is.
- A young boy dies in a traffic accident, while another child needs a heart transplant, but the father of the deceased boy does not want to donate his son's heart.
- A wife comes to see her husband only to find out he has a secret boyfriend visiting him. Diane agrees to go on a date with Steve. When a patient does not want to press charges of rape, Danny storms off because of the injustice of it.