- Forward for Bella Vista de Bahía Blanca (2001-02), Huracán de Tres Arroyos (2002-03), C.A. Banfield (2004), Boca Juniors (2005-09), Genoa C.F.C. (2009-12), Inter Milan (2012-17) and Bologna F.C. 1909 (2017-).
- 27 appearances for Argentina National Football Team (2005-2014); scored 3 goals. Member of the Copa América 2007, and the Germany '06 and the Brazil '14 squads.
- His father José Ramón Palacio is former soccer player.
- Won the Argentine Primera División (2005 Apertura, 2006 Clausura, 2008 Apertura); Recopa Sudamericana (2005, 2006, 2008); Copa Sudamericana (2005); Copa Libertadores (2007) with Boca Juniors.
- Has a daughter called Juana born on May 11, 2010.
- Scored goals for Boca Juniors during the finals matches of the Copa Sudamericana (2005), Recopa Sudamericana (2006 and 2008), Copa Libertadores (2007) and FIFA Club World Cup (2007).
- Was named in the South America Team of the Year in 2005 and 2006.
- Top scorer of the Argentine Primera División (2006 Apertura).
- Member of the Argentina National team who finished runners-up of the 2007 Copa América and the 2014 FIFA World Cup.
- Won the Bronze Ball at the 2007 FIFA Club World Cup.
- Won the Jorge Newbery Gold Award (by Government of the City of Buenos Aires) in 2008.
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