- After finding out that HBO didn't put her name forward for an Emmy Award consideration (for her role of Brienne in Game of Thrones (2011)), she did it herself and received a nomination in the category "Best Supporting Actress in a Drama Series". She explained that she did it for the character and what she feels she represents.
- Several inches taller than towering leading ladies like Uma Thurman and Sigourney Weaver, she is one of a small handful of professional actresses with a successful film & TV career who stands over 6 feet tall. Another is fellow Brit Janet McTeer, who is 6' 1" (1,86 m), and Australian Elizabeth Debicki, who is 6' 2¾" (1,9 m).
- A lifelong fan of Madonna, while filming S2 of Top of the Lake (2013) in Australia, Gwendoline received an invitation text from Madonna's manager Guy Oseary to attend the final leg of her 2016 "Rebel Heart Tour" in Sydney. Not only did she attend, but she was invited onstage to perform alongside her idol.
- Weirdest fan encounter occurred in a restaurant when she visited the ladies' room. No sooner was she seated on the 'throne' when a woman's hand reached in under the cubicle door with a phone and a vocal request for a selfie.
- During an interview with Radio Times, she claimed that she and her mother had "lost track" of her age. Her comment was likely an exaggeration, as business records filed by her company, Christie Ventures Ltd, state she was born in 1978.
- Romantically involved with longtime partner and fashion designer Giles Deacon. (2023)
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