- Goalkeeper for Parma Calcio 1913 (1995-2001, 2021-), Juventus F.C. (2001-2018, 2019-2021) and Paris Saint-Germain (France, 2018-19).
- Member of the Italy national team who won the 2006 FIFA World Cup; runner-up of the 2012 UEFA European Championship.
- He was engaged to his wife Alena Seredova from 2005 to their marriage in 2011.
- December 28th, 2007: his fiancée (now ex-wife) Alena Seredova gave birth to her and Gigi's first child, a boy named Louis Thomas. He was named in honor of Thomas N'Kono, a Cameroonian retired goalkeeper.
- Member of the Italy youth team who won the 1996 UEFA European U21 Championship.
- October 31st, 2009: his fiancée (now ex-wife) Alena Seredova gave birth to her and Gigi's second child, a boy named David Lee.
- He has declared that he decided to be a goalkeeper after seeing Thomas N'Kono's performances at the 1990 FIFA World Cup. N'Kono was a Cameroonian goalkeeper, considered one of the best African goalkeepers of all time.
- He comes from a family of Italian athletes. His mother, Maria Stella, was a discus thrower and his father, Adriano, was a weightlifter. Gigi's two sisters, Veronica and Guendalina, played volleyball for the Italian National Volleyball Team. His uncle, Dante Masocco, was a basketball player who also represented the National Team.
- Is in a relationship with Ilaria D'Amico since 2014. They have a son together.
- January 6, 2016: his girlfriend Ilaria D'Amico gave birth to her son named Leopoldo Mattia Buffon.
- 176 appearances for Italy National Football Team (1997-2018). Member of the Euro 2004, 2008, 2012, 2016, and the World Cup 1998, 2002, 2006, 2010, and 2014 squads.
- Honours with Parma Calcio 1913: UEFA Cup (1999); Coppa Italia (1999); Supercoppa Italiana (1999). Honours with Juventus F.C.: 10 Serie A (2001, 2003, 2012-2018, 2020); 6 Supercoppa Italiana (2002, 2003, 2012, 2013, 2015, 2020); 5 Coppa Italia (2015-2018, 2021); Serie B (2007).
- Won the 1999 Bravo Award.
- Won the Serie A Goalkeeper of the Year award twelve times (1999, 2001-2003, 2005, 2006, 2008, 2012, 2014-2017).
- Won the UEFA Club Footballer of the Year award in 2003.
- Named in the UEFA Team of the Year five times (2003, 2004, 2006, 2016, 2017).
- Named in the ESM Team of the Year in 2002/03 and 2016/17.
- Won the Best European Goalkeeper award three times (2003, 2016, 2017).
- Named the IFFHS World's Best Goalkeeper five times (2003, 2004, 2006, 2007, 2017).
- 2004: One of FIFA 100 by Pelé.
- Named in the 2006 FIFA World Cup All-Star Team.
- Named in the FIFA FIFPro World XI three times (2006, 2007, 2017).
- Named in the UEFA Euro Team of the Tournament in 2008 and 2012.
- In 2009, named in the Team of the Decade by ESPN and Sports Illustrated.
- Named the IFFHS Best Goalkeeper of the Decade (2001-2011).
- Named the IFFHS Best Goalkeeper of the 21st Century (2001-2020).
- Named in the Serie A Team of the Year five times (2012, 2014-2017).
- Won the Pallone Azzurro in 2013 and 2016.
- Named in the UEFA Europa League Squad of the Season in 2013/14.
- Named in the UEFA Champions League Squad of the Season two times (2014/15 and 2016/17).
- Named in the UEFA Euro All-time XI in 2016.
- Won the 2016 Premio Nazionale Carriera Esemplare "Gaetano Scirea".
- Won the 2016 Golden Foot.
- Named the Serie A Footballer of the Year in 2016/17.
- Won The Best FIFA Goalkeeper in 2017.
- Named in the IFFHS Men's World Team in 2017.
- Won the 2017 Gazzetta Sports Award as the Man of the Year.
- Named in the Juventus Greatest XI of All Time in 2017.
- Captain of Juventus F.C. from 2012-2018.
- Holds the most appearances, penalties saved and the clean sheets for Italy national team.
- Captain of Italy National Football Team from 2012-2018.
- Played well over 650 games at Serie A.
- Played well over 650 games for Juventus F.C..
- Named in the Ballon d'Or Dream Team (Silver) in 2020.
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